par Fruhling, Janos ;Sand, G;Penasse, Willy
Référence Journal of Ultrastructure Research, 44, 1-2, page (113-133)
Publication Publié, 1973
Article révisé par les pairs
Résumé : The intracellular volume occupied by the liposomes, mitochondria, and endoplasmic reticulum was determined in the zona fasciculata of guinea pig, rat, and beef adrenal cortex, by stereological analysis. These results were compared with the determined quantities of free and esterified cholesterol, triglycerides, and phospholipids in isolated adrenal cortex and with the capacity of cholesterol synthesis in the adrenal cortex of the 3 species studied. It is concluded that in the fasciculata cells of adrenals where the endogeneous synthesis of cholesterol remains small (guinea pig, rat), one finds a great number of liposomes which contain large amounts of esterified cholesterol and triglycerides. In contrast there are few liposomes in the adrenal glands which have an important endogeneous synthesis of cholesterol; the quantities of esterified cholesterol and triglycerides are very low. The quantities of free cholesterol and phospholipids are similar in the 3 species.