Article révisé par les pairs
Résumé : Forty unselected cleft lip and cleft palate patients were divided into 2 groups. Using a double blind test method, local infiltration was performed with adrenalin + xylocaine in group I and POR 8 in group 11. Heart arrhythmia did not occur in either of the two groups. A 20 to 50 percent increase in blood pressure and heart rate was observed after adrenalin infiltration. Less than 20 percent increase was observed after POR 8 infiltration. Bleeding was equivalent in the cleft palate group but there was some more bleeding with POR 8 in the cleft lip group. However, troublesome postoperative bleeding was observed in 4 cases of cleft palate after adrenalin infiltration, one of them requiring reintubation. This observation and the absence of side effects of POR 8 justify for us the routine use of this drug in cleft palate surgery. © 1987 Springer-Verlag.