par Pelc, Isidore
Référence L'Encéphale, 2, 4, page (349-361)
Publication Publié, 1976
Article révisé par les pairs
Résumé : The use of sulpirid in psychiatry allows one to delineate 3 types of activity of this compound whose originality consists mainly in this triple association: neuroleptic activity, as well as anticonfusional and antidepressive. The psychodynamic and phenomenological evaluation of patients receiving a sulpirid treatment, has led to the consideration that the process of 'psychic decompensation' as a target variable particularly sensitive to the action of this psychotropic drug. This process can be found in various pathological states - acute delirious states, depressive episodes, anxiety, autism, stress situation - where sulpirid acts, beside its specific thymoanaleptic or neuroleptic properties, through an 'aspecific recompensation activity'. This translates, psychopathologically, the action of sulpirid on the vegetative brain as well as the anti stress properties of this psychotropic drug, as verified in animal experiments.