par D'Hollander, Alain ;Delcroix, Claude
Référence Acta Anaesthesiologica Belgica, 31, SUPPL., page (249-250)
Publication Publié, 1980
Article révisé par les pairs
Résumé : A pharmacodynamic model for neuromuscular blocking agents (N.M.B.A.) has been elaborated utilizng N.M.B.A. pharmacokinetics as a function generator. The model allows the determination of the ligand receptor relationship and T.H. value in relation to fractional receptor occupation. Data from the literature, experimental results and original clinical observations have been used to test the accuracy and validity of the model.