Ambulatory blood pressure lowering effects of butizide/potassium canrenoate in hypertensive patients
par Dupont, Alain;Van der Niepen, Patricia;Vanhaelst, Luc
Référence Current therapeutic research, 40, 6, page (990-997)
Publication Publié, 1986
Référence Current therapeutic research, 40, 6, page (990-997)
Publication Publié, 1986
Article révisé par les pairs
Résumé : | A double-blind, randomized, balanced, placebo-controlled study was conducted to assess the hypotensive and metabolic effects of a fixed combination of 5 mg of butizide and 50 mg of potassium canrenoate in 20 patients with mild-to-moderate essential hypertension. This treatment significantly reduced both clinic and ambulatory blood pressure and was well tolerated. Hypokalemia developed in only one patient. There were no other clinically significant metabolic side effects. |