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Design and implementation of a prototype Human Protein Index.

par Taylor, J;Anderson, N L;Scandora, A E;Willard-Gallo, Karen ;Anderson, N G
Référence Clinical chemistry, 28, 4 Pt 2, page (861-866)
Publication Publié, 1982-04

Article révisé par les pairs

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Résumé :

This paper describes information-handling aspects of the TYCHO I analysis system (Clin, Chem. 27: 1807--1820, 1981), which analyzes two-dimensional electrophoresis gels, matches the individual protein spots with those in a reference pattern, and stores various information--including spot measurements, identifications, treatment profiles, set memberships, and comments--in a computerized database. This and additional information such as amino acid composition and cellular localization is then accessible from an interactive program that includes a pictorial user interface and presents much of the data in graphical form. Use of the TYCHO I system is illustrated by examples drawn from analyses of gel patterns from human leukocytes.