par Weyens, Guy;Roovers, Martine;Glansdorff, Nicolas
;Charlier, Daniel;Pierard, André 
Référence Journal of Molecular Biology, 204, 4, page (1045-1048)
Publication Publié, 1988-12


Référence Journal of Molecular Biology, 204, 4, page (1045-1048)
Publication Publié, 1988-12
Article révisé par les pairs
Résumé : | Translation of the carA gene is efficiently initiated at the intrinsically weak UUG codon. A single nucleotide substitution changing the Shine-Dalgarno box of carA (GGAGG) into the sequence TGAGG reduces translation of carA sevenfold. This result supports the view that extensive complementarity between the Shine-Dalgarno sequence and 16 S RNA contributes significantly to the efficiency of translation when the latter starts at a weak initiation triplet. © 1988. |