par Ledoux, Lucien 
Référence Biochimica et biophysica acta, 23, C, page (121-127)
Publication Publié, 1957
Référence Biochimica et biophysica acta, 23, C, page (121-127)
Publication Publié, 1957
Article révisé par les pairs
| Résumé : | Ribonuclease is spontaneously inactivated in the presence of atmospheric oxygen. This inactivation can be suppressed by reduced glutathione or cyteine. New forms of the protein appear during the oxidation process. These forms, which are separable by chromatography, have low enzymic activity; they can be activated by reducing agents. The oxidizability of the samples is very variable and apparently depends on their initial state. The presence of reduced glutathione or gelatin prevents oxidation, dilution of the solution favours it. The results confirm the hypothesis that RNase contains sluggish S- groups, essential for an important part of the enzymic activity. © 1957. |
