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Global histone deacetylase enzymatic activity is an independent prognostic marker associated with a shorter overall survival in chronic lymphocytic leukemia patients.

par Van Damme, Michaël ;Crompot, Emerence ;Meuleman, Nathalie ;Mineur, Philippe;Dessars, Barbara ;El Housni, Hakim ;Bron, Dominique ;Lagneaux, Laurence ;Stamatopoulos, Basile
Référence Epigenetics, 9, 10, page (1374-1381)
Publication Publié, 2014

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Titre:	Global histone deacetylase enzymatic activity is an independent prognostic marker associated with a shorter overall survival in chronic lymphocytic leukemia patients.
Auteur:	Van Damme, Michaël; Crompot, Emerence; Meuleman, Nathalie; Mineur, Philippe; Dessars, Barbara; El Housni, Hakim; Bron, Dominique; Lagneaux, Laurence; Stamatopoulos, Basile
Informations sur la publication:	Epigenetics, 9, 10, page (1374-1381)
Statut de publication:	Publié, 2014
Sujet CREF:	Hématologie
Mots-clés:	B2M, Beta-2-microglobulin
	BCR, B cell receptor
	CLL, Chronic lymphocytic leukemia
	FCR Fludarabine-cyclophosphamide-rituximab
	HDAC
	HDAC, Histone deacetylase
	HDACi, HDAC inhibitor
	HR Hazard ratio
	IgHV, Immunoglobulin heavy-chain variable-region
	LDT, Lymphocyte doubling time
	LPL, Lipoprotein lipase
	MSC, Mesenchymal stromal cell
	NF-κB, Nuclear factor κB
	OS, Overall survival
	SAHA, Suberoylanilide hydroxamic acid
	SIRT, Sirtuin
	Sirtuin
	TFS, Treatment-free survival
	VPA, Valproic acid
	ZAP70, Zeta-chain-associated protein kinase 70
Note générale:	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:1559-2294
	info:doi/10.4161/15592294.2014.969628
	info:scp/84922019010
	info:pmid/25437053