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PET/CT with 18F-FDG- and 18F-FBEM-labeled leukocytes for metabolic activity and leukocyte recruitment monitoring in a mouse model of pulmonary fibrosis

par Bondue, Benjamin ;Sherer, Félicie ;Van Simaeys, Gaëtan ;Doumont, Gilles ;Egrise, Dominique ;Yakoub, Yousof;Huaux, François;Parmentier, Marc ;Rorive, Sandrine ;Sauvage, Sébastien ;Lacroix, Simon ;Vosters, Olivier ;De Vuyst, Paul ;Goldman, Serge
Référence The Journal of nuclear medicine, 56, 1, page (127-132)
Publication Publié, 2015-01

Article révisé par les pairs

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Résumé :

Idiopathic pulmonary fibrosis is characterized by a progressive and irreversible respiratory failure. Validated noninvasive methods able to assess disease activity are essential for prognostic purposes as well as for the evaluation of emerging antifibrotic treatments.