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Action of levorenine and papaverine on the local cerebral blood flow after chronic sylvian artery obstruction in the cat: preliminary report

par Capon, André ;Noterman, Jacques ;Demarteau, M.
Référence Acta neurologica belgica, 73, 6, page (384-388)
Publication Publié, 1973

Article révisé par les pairs

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Résumé :

The right sylvian artery was clipped in 20 cats. The neurological signs were checked during the postoperative period (mean duration 16 days). The volume of the softened brain was estimated post mortem). In 4 of these animals, the local cerebral blood flow recorded with thermodiffusion probes allowed a comparison between a softened region and the control hemisphere. It was shown that the passive increase in flow in response to the injection of levorenine was larger in the diseased brain (lack of autoregulation), and that the response to papaverine was either a rise in flow smaller than in the control hemisphere or a decrease in flow ('Steal phenomenon').