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Congenital varicella zoster infection related to maternal disease in early pregnancy

par Dodion Fransen, J.;Dekegel, Daniel ;Thiry, Lise
Référence Scandinavian journal of infectious diseases, 5, 2, page (149-153)
Publication Publié, 1973

Article révisé par les pairs

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Résumé :

Varicella in a newborn with scarring cutaneous lesions and symptoms of neurological damage occurred following maternal varicella at the 14th-19th wk of pregnancy. A high titer of complement fixing antibodies to varicella virus was found at birth, decreasing to a low level at 6 mth of age and then increasing. Neutralizing antibodies to herpes simplex viruses types I and II were not present. Electron microscopy demonstrated viral particles of the herpes group in the fluid of a zoster vesicle in the 10th wk of life. Neuromotor disturbances affecting deglutition resulted in recurring aspiration pneumonia, malnutrition, marasmus and death.