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The synthetic gestagen Levonorgestrel disrupts sexual development in Xenopus laevis by affecting gene expression of pituitary gonadotropins and gonadal steroidogenic enzymes.

par Lorenz, Claudia;Contardo-Jara, Valeska;Trubiroha, Achim ;Krüger, Angela;Viehmann, Viola;Wiegand, Claudia;Pflugmacher, Stephan;Nützmann, Gunnar;Lutz, Ilka;Kloas, Werner
Référence Toxicological sciences : an official journal of the Society of Toxicology, 124, 2, page (311-319)
Publication Publié, 2011-12

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Titre:	The synthetic gestagen Levonorgestrel disrupts sexual development in Xenopus laevis by affecting gene expression of pituitary gonadotropins and gonadal steroidogenic enzymes.
Auteur:	Lorenz, Claudia; Contardo-Jara, Valeska; Trubiroha, Achim; Krüger, Angela; Viehmann, Viola; Wiegand, Claudia; Pflugmacher, Stephan; Nützmann, Gunnar; Lutz, Ilka; Kloas, Werner
Informations sur la publication:	Toxicological sciences : an official journal of the Society of Toxicology, 124, 2, page (311-319)
Statut de publication:	Publié, 2011-12
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	3-Oxo-5-alpha-Steroid 4-Dehydrogenase -- genetics
	Animals
	Female
	Follicle Stimulating Hormone, beta Subunit -- genetics
	Gene Expression Regulation, Developmental -- drug effects
	Gene Expression Regulation, Enzymologic -- drug effects
	Gonadotropins -- genetics
	Gonads -- drug effects -- embryology -- enzymology -- pathology
	Larva -- drug effects -- growth & development -- metabolism
	Levonorgestrel -- adverse effects
	Luteinizing Hormone, beta Subunit -- genetics
	Male
	Pituitary Gland -- drug effects -- embryology -- metabolism
	Polymerase Chain Reaction
	Progestins -- adverse effects
	Sexual Development -- drug effects -- genetics
	Xenopus laevis
Langue:	Anglais
Identificateurs:	urn:issn:1096-0929
	info:doi/10.1093/toxsci/kfr241
	info:pii/kfr241
	info:pmid/21914719