par Zinga, B.;Lescrainier, Jean Paul ;Longo-Mbenza Ben-I-Sasa, Benjamin
Référence JEMU. Journal d'échographie et de médecine ultra-sonore, 20, 5-6, page (268-271)
Publication Publié, 1999-12
Article révisé par les pairs
Résumé : Objectives: To determine endometrial thickness, uterine and endometrial blood flow in postmenopausal women receiving hormone replacement therapy (HRT). Study design: forty hundred forty eight women were divided into six groups based on HRT. The endometrial thickness of all of them were examinated with Aloka 2000 and pulsatility and resistance index of uterine and endometrial arteries (if visible) were calculated. P < 0.05 was considered as significative. Result: The endometrial thickness was 2.8 mm ± 2.6 in group without HRT (n = 168), this endometrial thickness was significatively (p < 0.0001) lower than group with oestrogen alone: 8.7 mm ± 6, HRT sequential: 6.7 mm ± 3, HRT continous: 4 mm ± 3.1 (p<0.01), Progestagen alone: 8 mm ± 5.8 and Tibolone 6.7 mm ± 4. The mean RIs and PIs of uterine arteries are significantly lower in women receiving HRT (group 2-6) than women without HRT (0.72 ± 0.12 versus 0.92 ± 0.01) p < 0.01 and 2.16 ± 0.8 versus 2.46 ± 0.8 p < 0.01. The endometrial PI of 1.17 ± 0.4 in the HRT group was not significantly different from that in the no HRT group (1.85 ± 0.4) p = 0.06. Conclusion: The endometrial thickness was considerably lower with continous hormone replacement therapy around 4 mm. Moderate endometrial blood flow were present in all groups. The color doppler ultrasound reflects the hormonal status and change in the uterine and endometrial perfusion depending on hormonal therapy.