par Orloff, Serge ;Velidi Hanumantha, Rao ;Verbruggen, Leon A;Wagner, Jacques
Référence Acta orthopaedica Belgica (Ed. bilingue), 40, 5-6, page (726-734)
Publication Publié, 1974
Article révisé par les pairs
Résumé : The urinary hydroxyproline in patients after a replacement of the hip or knee joint remains elevated during 5 weeks, then returns progressively to normal values after 8 months. The nondialysable fraction of urinary hydroxyproline rises from the first hours following a mechanical and thermal aggression on the bone. The intravenous injection of heterologous denatured collagen is rapidly followed by an important excretion of degradation products of this molecule. It could be useful to closely follow the clinical evolution in patients presenting an abnormal urinary hydroxyproline excretion after hip or knee joint replacement. In effect, this could be a supplementary diagnostic test in case of loosening of the prosthesis.