Label-free imaging of cerebral beta-amyloidosis with extended-focus optical coherence microscopy

Bolmont, T; Bouwens, Arno; Pache, Christophe; Dimitrov, M; Berclaz, Corinne; Villiger, Martin; Wegenast-Braun, B.; Lasser, Theo; Fraering, P

Recherche avancée | Historique de recherche Mon DI-fusion | À propos de DI-fusion | Contact |

Citer

Label-free imaging of cerebral beta-amyloidosis with extended-focus optical coherence microscopy

par Bolmont, T ;Bouwens, Arno

;Pache, Christophe ;Dimitrov, M ;Berclaz, Corinne ;Villiger, Martin ;Wegenast-Braun, B.;Lasser, Theo ;Fraering, P
Référence Journal of Neuroscience, 32, 42, page (14548-14556)
Publication Publié, 2012

Article révisé par les pairs

Résumé :

We demonstrate label-free imaging of cerebral $beta$-amyloidosis ex vivo and in a living mouse model of Alzheimer's disease using extended-focus Fourier domain optical coherence microscopy (xfOCM). xfOCM provides 3D, high-resolution images of individual $beta$-amyloid plaques in the brain parenchyma and vasculature and requires no staining of the Alzheimeric sample under investigation. xfOCM also opens the possibility to perform minimally invasive studies of $beta$-amyloid pathology in vivo, without the use of labeling methods, which potentially confound experimental findings.

Documents en relation

DI-fusion

Machine learning for hand pose classification from phasic and tonic EMG signals during bimanual activities in virtual reality
par Simar, Cédric , Colot, Martin , Cebolla Alvarez, Ana Maria , Petieau, Mathieu , Chéron, Guy , Bontempi, Gianluca
Publication 2024-04-01
Clinical profile of patients with primary Sjögren's syndrome with non-identified antinuclear autoantibodies
par Parisis, Dorian , Sarrand, Julie , Cabrol, Xavier , Delporte, Christine , Soyfoo, Muhammad Shahnawaz
Publication 2024-04-30
Ionizing radiation responses appear incidental to desiccation responses in the bdelloid rotifer Adineta vaga
par Moris, Victoria , Bruneau, Lucie , Berthe, Jérémy , Heuskin, Anne-Catherine , Penninckx, Sébastien , Ritter, Sylvia , Weber, Uli , Durante, Marco , Danchin, Etienne E.G.J. , Hespeels, Boris , Doninck, Karine Van
Publication 2024-12
Core-shell structured microneedles with programmed drug release functions for prolonged hyperuricemia management
par Wang, Rui , Sun, Yanfang , Wang, Han , Liu, Tianqi , Shavandi, Amin , Nie, Lei , Yunusov, Khaydar , Jiang, Guohua
Publication 2024-01-01
Advanced PEG-tyramine biomaterial ink for precision engineering of perfusable and flexible small-diameter vascular constructs via coaxial printing
par Siminska-Stanny, Julia , Nicolas, Lise L.N. , Chafaï, Adam , Jafari, Hafez , Hajiabbas, Maryam , Dodi, Gianina , Gardikiotis, Ioannis , Delporte, Christine , Nie, Lei , Podstawczyk, Daria , Shavandi, Amin
Publication 2024

Référencement	Visibilité	Pérennité	Facilité
Les publications encodées constituent la bibliographie académique de l'Université.	Les documents déposés sont indexés par les moteurs de recherche (Google Scholar,…).	Les documents déposés en open-access sont archivés au sein du réseau de préservation SAFE-PLN (www.safepln.org).	Les listes de publications sont compatibles avec le CV-ULB, le FNRS et accessibles sur le web.