Article révisé par les pairs
Titre:
  • Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): Survival outcomes of a randomised, open-label, multicentre, phase 3 trial and their association with pathological complete response
Auteur:de Azambuja, Evandro; Abdel Azim, Hatem Hamdy; Holmes, Andrew A.P.; Holmes, Eileen; Piccart-Gebhart, Martine; Di Cosimo, Serena; Swaby, Ramona R.F.; Untch, Michael; Jackisch, Christian; Lang, Istvan; Smith, Ian; Boyle, Frances; Xu, Binghe; Barrios, Carlos; Perez, Edith A; Kim, Sung-Bae; Kuemmel, Sherko; Huang, Chiun Sheng; Vuylsteke, Peter; Hsieh, Ruey Kuen; Gorbunova, Vera; Eniu, Alexandru; Dreosti, Lydia; Tavartkiladze, Natalia; Gelber, Richard; Eidtmann, Holger; Baselga, José
Informations sur la publication:Lancet oncology, 15, 10, page (1137-1146)
Statut de publication:Publié, 2014
Sujet CREF:Cancérologie
MeSH keywords:Administration, Oral
Adult
Aged
Antibodies, Monoclonal, Humanized -- adverse effects -- therapeutic use
Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
Breast Neoplasms -- drug therapy -- metabolism -- mortality -- pathology
Chemotherapy, Adjuvant
Confidence Intervals
Disease-Free Survival
Dose-Response Relationship, Drug
Drug Administration Schedule
Female
Follow-Up Studies
Humans
Infusions, Intravenous
Maximum Tolerated Dose
Middle Aged
Neoadjuvant Therapy
Neoplasm Invasiveness -- pathology
Neoplasm Staging
Quinazolines -- adverse effects -- therapeutic use
Receptor, ErbB-2 -- metabolism
Survival Analysis
Treatment Outcome
Note générale:SCOPUS: ar.j
Langue:Anglais
Identificateurs:urn:issn:1470-2045
info:doi/10.1016/S1470-2045(14)70320-1
info:pii/S1470204514703201
info:scp/84908602324
info:pmid/25130998

Documents en relation

DI-fusion

  • Association of statin use on survival outcomes of patients with early-stage HER2-positive breast cancer in the APHINITY trial
    par Maurer, Christian , Agostinetto, Elisa , Ameye, Lieveke , Lambertini, Matteo Md Phd M. , Martel, Samuel , Pondé, Noam , Brandao, Marianna , Poggio, Francesca , Ferreira, Arlindo A.R. , Schiff, Rachel , De Angelis, Carmine , Gelber, Richard , Dent, Susan , Thomssen, Christoph , Piccart-Gebhart, Martine , de Azambuja, Evandro
    Publication 2025-07
  • Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer.
    par Audisio, Alessandro , Gallio, Chiara , Velenik, Vaneja , Meillat, Hélène , Ruiz-Garcia, Erika , Riesco, Maria Carmen , Alecha, Javier Suárez , Rasschaert, Gertjan , Carvalho, Carlos , Randrian, Violaine , Kirac, Iva , Hernando, Jorge , Artaç, Mehmet , O'Connor, Juan Manuel , Waldhorn, Ithai , Braam, Pètra Manou , Shamseddine, Ali , Moretto, Roberto , De la Pinta, Carolina , De Felice, Francesca , Dulskas, Audrius , Páez López-Bravo, David , Vanden Bulcke, Alexander , Bock, Felix , Deleporte, Amélie , Van Den Eynde, Marc , Geboes, Karen Paula , Loi, Mauro , Messina, Marco , Houlzé-Laroye, Constance , Puccini, Alberto , Pastorino, Alessandro , Papamichael, Demetris , Fiore, Michele , Sur, Daniel , Eid, Michal , Antoun, Claire , Salati, Massimiliano , Garajovà, Ingrid , Jakubauskas, Matas , Tomášek, Jirí , Sousa Pinto, Cidália Maria , Schwingel, Jerome , Morano, Federica , Adams, Richard A , Dermine, Alexandre , Chau, Amélie , Javed, Muhammad Ahsan , Ghidini, Michele , Fiorica, Francesco , Montenegro, Paola , Petrillo, Angelica , Spolverato, Gaya , Mulet Margalef, Núria , Diaz, Marie , Baratelli, Chiara , Puleo, Francesco , Karampeazis, Athanasios , Sert, Fatma , Gilliaux, Quentin , De Stefano, Alfonso , Liberale, Gabriel , Moretti, Luigi , Martinive, Philippe , Deltuvaite Thomas, Vaiva , Staggs, Vincent , Saad, Everardo Delforge , Van Laethem, Jean-Luc , Sclafani, Francesco , International Real-World TNT Study Consortium
    Publication 2025-09-01
  • Timing of Recurrence after Neoadjuvant Chemo-Immunotherapy in Patients with Early-Stage Triple-Negative Breast Cancer.
    par Licata, Luca , Mariani, Marco , Viale, Giulia , Dent, Rebecca Alexandra R. , Tolaney, Sara M , Schmid, Peter , Hamilton, Erika , Sotiriou, Christos , Pusztai, Lajos , Bianchini, Giampaolo
    Publication 2025-09
  • Identification of HER2-positive breast cancer molecular subtypes with potential clinical implications in the ALTTO clinical trial
    par Rediti, Mattia , Venet, David , Joaquin Garcia, Andrea , Maetens, Marion M. , Vincent, Delphine , Majjaj, Samira , El-abed, Sarra , Di Cosimo, Serena , Ueno, Takayuki , Izquierdo, Miguel , Piccart-Gebhart, Martine , Pusztai, Lajos , Loi, Sherene , Salgado, Roberto , Viale, Giuseppe , Rothé, Françoise , Sotiriou, Christos
    Publication 2024-12-01
  • Association of HER2-low with clinicopathological features in patients with early invasive lobular breast cancer: an international multicentric study
    par Van Baelen, Karen , Nguyen, Ha Linh , Richard, François , Zels, Gitte , Karsten, Maria Margarete , Marta, Guilherme Nader , Vermeulen, Peter B. , Dirix, Luc Y , Dordevic, Adam David , de Azambuja, Evandro , Larsimont, Denis , Maetens, Marion M. , Biganzoli, Elia , Wildiers, Hans , Smeets, Ann , Nevelsteen, Ines , Neven, Patrick , Floris, Giuseppe , Desmedt, Christine
    Publication 2025-12