Résumé : Tyrosine betaine, four new cardenolides (4, 5, 6, and 7) and three known cardenolides (2, 3, and 8) were isolated from the defensive secretion, of the leaf beetle Oreina gloriosa and their chemical structure determined. 16 secretion components of individual beetles were quantified. Secretion composition of field-collected beetles was affected by season, sex and body weight. © 1992 Birkhäuser Verlag.