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The action of enflurane (Ethrane) on cerebral blood flow

par Reinhold, Heinrich ;De Rood, Monique ;Capon, André ;Mouawad, Émile ;Fruhling, Janos ;Verbist, Adolf
Référence Acta Anaesthesiologica Belgica, 25, 2, page (257-265)
Publication Publié, 1974

Article révisé par les pairs

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Résumé :

Cerebral blood flow in the grey matter was measured by the 133Xenon method in 5 patients suffering from vascular brain lesion. A first measurement was performed under N 2O fentanyl anesthesia and a second under N 2O enflurane 1% anesthesia. For both tests the subjects were maintained under stable respiratory conditions and normocapnia by artificial ventilation. Enflurane 1% caused a reduction of cerebral blood flow in all 5 patients. The decrease varied between 5 and 23%, with a mean of 12%. The decrease of cerebral blood flow under enflurane is a favorable effect for its use in neurosurgery.