par Dejonckheere, Marc 
;Deloof, Thierry ;Dustin, Nele ;Ewalenko, Patricia
Référence European journal of anaesthesiology, 7, 5, page (421-427)
Publication Publié, 1990
;Deloof, Thierry ;Dustin, Nele ;Ewalenko, Patricia Référence European journal of anaesthesiology, 7, 5, page (421-427)
Publication Publié, 1990
Article révisé par les pairs
| Résumé : | Two-hundred patients scheduled for elective thyroidectomy under halothane-nitrous-oxide-oxygen anaesthesia were randomly divided into two equal groups and were blindly given either alizapride 100 mg i.v. or a placebo before induction of anaesthesia and every 4 h thereafter for 20 h. Occurrence of nausea or vomiting were recorded after each injection of the trial drug. The incidence of nausea (63.0% vs. 45.8%; P = 0.016) and vomiting (63.0% vs. 41.1%; P = 0.002) was significantly higher in the placebo group. No troublesome side-effects were imputed to the use of alizapride. Neither sex, nor clinical status, nor difficulty of tracheal intubation influenced the incidence of nausea or vomiting in this series. It is concluded that alizapride effectively reduces the occurrence of emetic sequelae after thyroidectomy. |
