Article révisé par les pairs
Résumé : Growth Hormone (GH) response to insulin induced hypoglycemia was compared in 21 normal subjects, 20 untreated primary hypothyroid and 19 untreated hyperthyroid patients. The statistical comparison of the results confirms the significant blunting of the GH response commonly encountered in hypothyroidism and also shows, a much less important but significant, decrease of the GH response in hyperthyroidism. Restoration of the euthyroid state in 9 of the previously hypothyroid patients enhanced significantly their GH responsiveness to values not significantly different from normal, whereas in 13 of the previously hyperthyroid patients the response did not change significantly. The possible meaning of the abnormal responses in untreated hypo and hyperthyroidism is discussed in the light of the results observed.