par Bastenie, Paul Auguste
Référence Acta cardiologica, 37, 5, page (365-373)
Publication Publié, 1982
Article révisé par les pairs
Résumé : In contrast to general opinion, hypothyroidism is not an infrequent disease: it affects 1.5% of the Western populations and 1/3 of the cases remain undiagnosed. Latent hypothyroidism, easily detected by the assay of circulating thyroid antibodies and graded by the estimation of serum TSH, is present in a further 3 to 5 per cent of the general population. Whereas overt hypothyroidism is a definite cause of vascular damage, the role of subclinical hypothyroidism as a risk factor of CHD remains debatable Several independent studies suggest that the importance of this role may depend on the presence or absence of other risk factors. Practically latent hypothyroidism should be looked for in all cases of unexplained hyperlipidaemia and in all women over the age of 50. In all cases with biological signs of grade III AAT, careful exploration of the cardiovascular state should be considered before substitutive therapy is started.