par Crabbe, Georges 
;Van Poucke, M.;Cantinieaux, Brigitte
Référence Clinical and Laboratory Haematology, 24, 3, page (179-182)
Publication Publié, 2002
;Van Poucke, M.;Cantinieaux, Brigitte Référence Clinical and Laboratory Haematology, 24, 3, page (179-182)
Publication Publié, 2002
Article révisé par les pairs
| Résumé : | Protein aggregates, red cell or white cell fragments are known to interfere with platelet counts in automated blood analysers, both by aperture impedance and optical technologies. When a falsely high value is suspected, interference by pseudo-platelet particles can be confirmed by systematic examination of stained blood films. The method that best avoids these sources of interference is the reference, immunological platelet count. We describe a case of treated malaria with a false normal platelet count. The blood smear revealed small red cells, infected by trophozoites of Plasmodium falciparum, that interfered with the platelet count. The Cell Dyn® 4000 shows different patterns of interference by infected red cells in its impedance and optical counts, and thrombocytopenia was suspected immediately. This was confirmed by a phase-contrast microscopic platelet count. |
