par Bosseler, Françoise 
;Pohl, Viviane ;Lievens, Andrée ;Rolin, Sylvie
Référence Radiation research, 68, 2, page (292-299)
Publication Publié, 1976
;Pohl, Viviane ;Lievens, Andrée ;Rolin, Sylvie Référence Radiation research, 68, 2, page (292-299)
Publication Publié, 1976
Article révisé par les pairs
| Résumé : | Different somatic cell hybrids have been studied as a function of their X ray survival and karyotypic properties. Hybrids between X ray sensitive mouse lymphoma cells and mouse fibroblasts, retaining a large proportion of both parental chromosomes, were much more resistant to irradiation than either of the parental cells. On the other hand, hybrids between sensitive mouse lymphoma cells and hamster fibroblasts which also retained a relatively high number of chromosomes from both parents had a sensitivity intermediate between the sensitivities of the parental cell lines. Finally, hybrids between mouse fibroblasts and hamster fibroblasts carrying at least one hamster genome and less than one mouse genome resembled the hamster parent with respect to survival capacity. The significance of these results is discussed. |
