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The peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer disease.

par Galas, Marie-Christine ;Dourlen, Pierre;Bégard, Séverine;Ando, Kunie ;Blum, David ;Hamdane, Malika ;Buée, Luc
Référence The Journal of biological chemistry, 281, 28, page (19296-19304)
Publication Publié, 2006-07

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Titre:	The peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer disease.
Auteur:	Galas, Marie-Christine; Dourlen, Pierre; Bégard, Séverine; Ando, Kunie; Blum, David; Hamdane, Malika; Buée, Luc
Informations sur la publication:	The Journal of biological chemistry, 281, 28, page (19296-19304)
Statut de publication:	Publié, 2006-07
Sujet CREF:	Biologie cellulaire
MeSH keywords:	Adaptor Proteins, Signal Transducing -- metabolism -- physiology
	Alzheimer Disease -- metabolism
	Animals
	Catalysis
	Enzyme Activation
	Enzyme Inhibitors -- pharmacology
	Hydrogen Peroxide -- pharmacology
	Microtubules -- metabolism
	Naphthoquinones -- pharmacology
	Neurons -- metabolism
	Peptides -- chemistry
	Phosphorylation
	Rats
	tau Proteins -- chemistry -- metabolism
Langue:	Anglais
Identificateurs:	urn:issn:0021-9258
	info:doi/10.1074/jbc.M601849200
	info:pii/M601849200
	info:pmid/16675464