Article révisé par les pairs
Titre:
  • Design and evaluation of a 6-mer amyloid-beta protein derived phage display library for molecular targeting of amyloid plaques in Alzheimer's disease: Comparison with two cyclic heptapeptides derived from a randomized phage display library.
Auteur:Larbanoix, Lionel; Burtea, Carmen; Ansciaux, Emilie; Laurent, Sophie; Mahieu, Isabelle; Vander Elst, Luce; Muller, Robert
Informations sur la publication:Peptides, 32, 6, page (1232-1243)
Statut de publication:Publié, 2011-06
Sujet CREF:Sciences bio-médicales et agricoles
MeSH keywords:Alzheimer Disease -- drug therapy -- genetics -- metabolism -- pathology
Amino Acid Sequence
Amyloid beta-Peptides -- chemistry -- genetics -- metabolism
Animals
Biotinylation
Blood-Brain Barrier -- metabolism -- pathology
Contrast Media
Disease Models, Animal
Enzyme-Linked Immunosorbent Assay
Humans
Kinetics
Magnetic Resonance Imaging -- methods
Mice
Mice, Transgenic
Models, Molecular
Molecular Sequence Data
Molecular Targeted Therapy
Mutagenesis, Site-Directed
Peptide Fragments -- chemistry -- genetics -- metabolism -- pharmacology
Peptide Library
Peptides, Cyclic -- chemistry -- genetics -- metabolism -- pharmacology
Plaque, Amyloid -- drug therapy -- metabolism -- pathology
Protein Binding -- drug effects
Sequence Analysis, DNA
Thiazoles -- analysis
Note générale:Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langue:Anglais
Identificateurs:urn:issn:0196-9781
info:doi/10.1016/j.peptides.2011.04.026
info:pii/S0196-9781(11)00175-6
info:pmid/21575663

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