par Brachet, Jean
Référence Experimental cell research, 48, 1, page (233-236)
Publication Publié, 1967-10
Article révisé par les pairs
Résumé : RNA and protein synthesis is required at all stages of maturation. Inhibitors of these syntheses do not prevent the appearance, after the breakdown of the nuclear membrane, of Feulgen positive bodies in the cytoplasm; but they prevent their migration-and that of the chromosomes-towards the animal cortex. Actinomycin produces a contraction of the chromosomes, while cycloheximide and puromycin tend to uncoil them. Contraction of the chromosomes, during meiosis, must be linked to changes in RNA and protein synthesis. After treatment with the inhibitors tested-especially with actinomycin-the nucleolus-associated chromatin becomes very conspicuous after Feulgen staining. © 1967.

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