Cytochemical study of human lymphocytes stimulated by PHA in function of donor age

Preumont, A M; Van Gansen, Paulette; Brachet, Jean

doi:doi/10.1016/0047-6374(78)90050-7

Recherche avancée | Historique de recherche Mon DI-fusion | À propos de DI-fusion | Contact |

Citer

Cytochemical study of human lymphocytes stimulated by PHA in function of donor age

par Preumont, A M ;Van Gansen, Paulette

;Brachet, Jean

Référence Mechanism of ageing and development, 7, 1, page (25-32)
Publication Publié, 1978-01

Article révisé par les pairs

Résumé :

The 3H-AM binding reflects the structural changes involved in the cellular differentiation. This parameter was studied during blastic transformation of human lymphocytes, in relation to the age of the donor. Although they are individual variations, the 3H-AM binding is higher in the young group than in the aged subjects, as well as the blast transformation score. These results indicate that the weak lymphocyte response to the mitogen lectine (PHA) stimulation could be related to some age-induced structural alterations of the chromatin, resulting in an irreversible blockage in G1, at least in some of the T lymphocytes.

Documents en relation

DI-fusion

Impact of provoked stress on model-free and model-based reinforcement learning in individuals with alcohol use disorder
par Wyckmans, Florent , Chatard, Armand , Kornreich, Charles , Gruson, Damien , Jaafari, Nematollah , Noël, Xavier
Publication 2024-12
BABINE: An original and user-friendly scale for the simple and quick management of herb-drug interactions in clinical practice
par Cnudde, Anthony , Allely, Camille A C , Biset, Natacha , Champy, Pierre , Fouilhe Sam-Lai, Nathalie , Huret, Fanny , Laxson, Sibi , Mercan, Aline AM , Noukela Noumi, Doris Pascale , Michalet, Serge , Montis, Andrea , Pochet, Stéphanie , Schils, Audrey , Tangeten, Cécilia , Tod, Michel , Van Antwerpen, Pierre , Vervacke, Audrey , Souard, Florence
Publication 2024-12-18
Evaluating MIR and NIR Spectroscopy Coupled with Multivariate Analysis for Detection and Quantification of Additives in Tobacco Products
par Akhtar, Zeb , Canfyn, Michaël , Vanhee, C. , Delporte, Cédric , Adams, Erwin , Deconinck, Eric
Publication 2024-11
A Case of Cryptogenic Organizing Pneumonia after Immunotherapy and Radiotherapy for a Stage IV Non-Small Cell Lung Cancer
par Fardeau, Emmanuel , Roelandts, Martine , Moretti, Luigi , Remmelink, Myriam , Stathopoulos, Konstantinos , Ruiz Patino, Maria Jose , Berghmans, Thierry , Van Houtte, Paul
Publication 2024-10-23
Involving patients by virtue of their experiential knowledge in research: recruitment and training in qualitative analysis in the ‘Symphony of Us’ project
par Horicks, Florence , Lalova-Spinks, Teodora TLS , Léonard, Silke SL , Boesten, Nadine NB
Publication 2024-11-04

Référencement	Visibilité	Pérennité	Facilité
Les publications encodées constituent la bibliographie académique de l'Université.	Les documents déposés sont indexés par les moteurs de recherche (Google Scholar,…).	Les documents déposés en open-access sont archivés au sein du réseau de préservation SAFE-PLN (www.safepln.org).	Les listes de publications sont compatibles avec le CV-ULB, le FNRS et accessibles sur le web.