par Gratia, Jean-Pierre
Référence Research in virology, 140, 4, page (373-388)
Publication Publié, 1989
Article révisé par les pairs
Résumé : Prophage Φ80 is used for the detection of "discrete" viruses such as phage Φγ by genetic recombination. Several genetic events have produced a series of hybrids which are currently being characterized. Characteristic genomic properties of the parent phages are recognized in these hybrids. "λ"-type phages contain a cos-ended DNA of a single sequence, the size of which may be altered by hybridization. "γ"-type phages contain DNA molecules of uniform size (about 52 kb) and of variable ends; their genome is able to promote highly efficient transduction (pug type) regardless of the origin of the right arm. In both hybrids, the att site is most often a junction point between the parental genomes due to common int-promoted recombination. New evidence is provided for the formation of viable heterozygous "λ/γ"-type bacteriophages. © 1989 Elsevier.