Prevention of febrile neutropenia in chemotherapy-treated cancer patients: Pegylated versus standard myeloid colony stimulating factors. Do we have a choice?

Klastersky, Jean; Awada, Ahmad

doi:doi/10.1016/j.critrevonc.2010.02.005

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Prevention of febrile neutropenia in chemotherapy-treated cancer patients: Pegylated versus standard myeloid colony stimulating factors. Do we have a choice?

par Klastersky, Jean

;Awada, Ahmad

Référence Critical reviews in oncology/hematology, 78, 1, page (17-23)
Publication Publié, 2011-04

Article révisé par les pairs

Résumé :

The pertinent literature on clinical studies comparing the respective value of myeloid colony stimulating factors to pegfilgrastim as a prevention of febrile neutropenia in chemotherapy-treated cancer patients has been reviewed. Pegfilgrastim is definitely not inferior to filgrastim or other myeloid colony stimulating agents with respect to duration of grade IV neutropenia and delivery of full chemotherapy dose on time; several comparative studies indicate a trend to less frequent febrile neutropenia with pegfilgrastim. © 2010 Elsevier Ireland Ltd.

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