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Dépistage néonatal des hémoglobinopathies dans la région bruxelloise

par Tshilolo, Léon;Gulbis, Béatrice ;Barlow, Patricia ;Damis, Eliane;Denis-Song, R.;Ferster, Alina ;Haumont, Dominique ;Vanderpas, Jean-Baptiste ;Pardou, Anne ;Schwers, Jean;Vokaer, Alain Patrick ;Vertongen, Françoise
Référence Revue médicale de Bruxelles, 18, 2, page (70-73)
Publication Publié, 1997-04

Article révisé par les pairs

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Résumé :

We realised this study in order to determine the frequency of abnormal haemoglobins and to appreciate the need for a neonatal screening for haemoglobinopathies in Brussels. Over a two year-period, 9575 cord blood samples were systematically screened. The study disclosed following results ' 40% of newborns were from regions at risk for haemoglobinopathies and abnormal haemoglobins were present in 2,5% of the neonates tested. This frequency is similar to those reported elsewhere m North Europe. The most frequent abnormal haemoglobins were the Hb S, Bart's, C, D and E. Three cases of severe forms of sickle cell anaemia were identified. The frequency of abnormal haemoglobins and Hb S traits combined to the high rats of mixed marriages (16%) justifies the need for a universal screening for haemoglobinopathies in Brussels.