Titre:
  • Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer
Auteur:Saini, Kamal; Loi, Sherene; Azambuja, Evandro; Metzger-Filho, Otto; Saini, Monika Lamba; Ignatiadis, Michail; Dancey, Janet J.E.; Piccart-Gebhart, Martine
Informations sur la publication:Cancer treatment reviews, 39, 8, page (935-946)
Statut de publication:Publié, 2013-12
Sujet CREF:Cancérologie
Imagerie médicale, radiologie, tomographie
Mots-clés:Breast cancer
Cross-talk
Dual inhibition
MAPK
MTOR
Personalized medicine
PI3K
Ras/Raf/MEK/ERK
Targeted therapy
MeSH keywords:Breast Neoplasms -- drug therapy -- enzymology
Female
Humans
Individualized Medicine
MAP Kinase Signaling System -- drug effects
Mitogen-Activated Protein Kinases -- genetics -- metabolism
Phosphatidylinositol 3-Kinase -- genetics -- metabolism
Proto-Oncogene Proteins c-akt -- genetics -- metabolism
TOR Serine-Threonine Kinases -- genetics -- metabolism
Note générale:SCOPUS: re.j
Langue:Anglais
Identificateurs:urn:issn:0305-7372
info:doi/10.1016/j.ctrv.2013.03.009
info:pii/S0305737213000728
info:scp/84883556505
info:pmid/23643661