par Nijs, Michelle ;Brassinne, Christiane;Coune, André ;Tagnon, Henri
Référence European journal of cancer & clinical oncology, 9, 9, page (691-698)
Publication Publié, 1973
Article révisé par les pairs
Résumé : Previous work had demonstrated a direct proteolytic activity of human prostatic extract on a substrate of casein but not of fibrinogen or fibrin. In the experiments reported here, with a substrate of fibrin or fibrinogen having a higher concentration and specific activity than in previous experiments, it was possible to demonstrate such a direct proteolytic activity on these substrates. In addition, the presence of atrypsin and plasmin inhibitor in prostatic extract could be demonstrated. By ammonium sulphate fractionation a fraction can be separated from the extract, containing the factor responsible for the direct proteolytic activity and the inhibitor.