• Citer

Empirical antimicrobial therapy with Timentin plus amikacin in febrile granulocytopenic cancer patients

par Meunier, Françoise ;Snoeck, Robert ;Lagast, Hjalmar
Référence Journal of antimicrobial chemotherapy, 17, SUPPL. C, page (195-201)
Publication Publié, 1986

Article révisé par les pairs

• Détails
• Contenu

Résumé :

Timentin (ticarcillin plus clavulanic acid) plus amikacin was administered as an empirical regimen to 52 febrile granulocytopenic patients with cancer and appeared as effective as the other commonly recommended combinations of antimicrobial agents. A favourable response was observed in 61% of episodes with bacteraemia and in 83% of the episodes without bacteraemia. However, the efficacy of Gram-positive bacteraemia was suboptimal and the emergence of superinfections caused by Gram-positive cocci may represent a clinical challenge.