par Thomas, René 
;Mousset, Suzanne
Référence Journal of Molecular Biology, 47, 2, page (179-191)
Publication Publié, 1970-01
;Mousset, Suzanne Référence Journal of Molecular Biology, 47, 2, page (179-191)
Publication Publié, 1970-01
Article révisé par les pairs
| Résumé : | Thermal induction of λc857-434hy and λc857-80hy tandem dilysogens results in replication not only of the λ, which is induced, but also of the other phage. Nevertheless, the latter remains under immunity control, since: (a) a superinfecting phage of that immunity fails to replicate; (b) the genes under direct immunity control are not expressed. Replication of the non-induced phage takes place only if it is adjacent to the λ, and only if the λ itself is able to replicate: however, this replication does not require that the replicative enzymes are interchangeable between λ and the other phage. Clearly, one deals here with passive replication of a phage, as a part of a λ-driven replicon. Function Int frequently excises the whole tandem of prophages, presumably as a double length circle. Replication from this structure, followed by the action of function Ter, accounts for our results as well as for those of Whitfleld & Appleyard (1958). The situation described here is in many respects similar to that analyzed by Gottesman & Yarmolinsky (1968). In their case, however, passive replication takes place in situ because int- mutations in the prophages prevent early excision, and particles of only one immunity are found in the yield. © 1970. |
