• Citer

Diorganotin derivatives of 2,6-dihydroxymethylpyridine and of 3-(N-pyrrolidino)-1,2-propanediol: Synthesis, characterization and in vitro antitumor activity

par Gielen, Marcel ;Boualam, Mohammed ;Biesemans, Monique;Mahieu, Bernard;Willem, Rudolph
Référence Heterocycles, 34, 3, page (549-559)
Publication Publié, 1992-03

Article révisé par les pairs

• Détails
• Contenu

Résumé :

Three diorganotin(IV) derivatives of 2,6-dihydroxymethylpyridine and 3-(N-pyrrolidino)-1,2-propanediol have been synthesized and characterized by Mössbauer spectroscopy, mass spectrometry and by 1H, 13C and 119Sn nmr. Their activities in vitro against two human tumor cell lines, MCF-7 and WiDr, are compared to those of cis-platin and doxorubicin. © 1992.