Résumé : PTFE samples were treated by low-pressure O2 RF plasmas. The adsorption of BSA was used as a probe for the protein-resistant properties. Exposure of PTFE to an O2 plasma leads to an increase in chamber pressure. OES reveals the presence of CO, CO2 and F in the gas phase, indicating a strong etching of the PTFE surface by the plasma. Furthermore, the high-resolution C1s spectra show CF3, CF and C-CF components. WCA as high as 160° were observed, indicating a super-hydrophobic behavior. AFM images of surfaces treated at high plasma power showed an increase in roughness. Lower amounts of BSA adsorption were detected on high power, O2 plasma-modified PTFE samples compared to low power, oxygen plasma-modified ones. A graph is presented. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.