par Peretz, Anne
Référence Arztliche Laboratorium, 36, 11, page (299-304)
Publication Publié, 1990
Article révisé par les pairs
Résumé : Selenium has immunostimulant properties which are rather well established in animals but poorly documented in humans. The present study was undertaken to explore the effects of in vivo selenium supplementation on some immune parameters of two population groups at risk for marginal selenium deficiency and impairment of the immune system: elderly institutionalized subjects and patients on total parenteral nutrition. An enhancement of the proliferative response to mitogens associated with a decreased suppressor effect of the serum was observed in the elderly; an increased response to mitogens, and to antigens was likewise noted in the other group. These results confirm in humans the role of selenium as an immune stimulant.