par Toussaint, Charles 
Référence JN. Journal of Nephrology, 11, SUPPL. 1, page (49-50)
Publication Publié, 1998-03
Référence JN. Journal of Nephrology, 11, SUPPL. 1, page (49-50)
Publication Publié, 1998-03
Article révisé par les pairs
| Résumé : | Owing to the rarity of PH, the efficacy of pyridoxine therapy has only been tested in very small series of patients. From two recent reports including 18 patients, 50% of patients would be unresponsive to pyridoxine whereas oxaluria would be normalized in 20% of patients and somewhat reduced - but not to normal level - in the remaining 30%. In a few aneodotical cases pyridoxine administration was reported to improve kidney function in patients with renal failure secondary to hyperoxaluria. It is reminded that megadoses of pyridoxine (0.5 to 6 g daily) may induce severe sensory neuropathy. |
