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Study of bone mineralization at the microscopic level using an electron probe microanalyser

par Wollast, Roland ;Burny, Franz Léon
Référence Calcified Tissue Research, 8, 1, page (73-82)
Publication Publié, 1971-12

Article révisé par les pairs

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Résumé :

Electron probe microanalysis is a recent technique for the study of bone and the conditions for the correct interpretation of the results are described. The Ca/P molar ratio was measured in normal and in three pathological bones. These measurements were carried out in different regions of cortical bone. The results are in agreement with the results obtained by microradiography. Microprobe analysis, however, allows the measurement of elements at the microscopic level. Electron probe microanalysis was used to study the distribution of sodium and magnesium in the interhaversian and haversian tissues of adult cortical bone. Observations show the heterogeneity of distribution of these elements. Concentrations are higher in young bone (osteons), in agreement with the hypothesis of ion absorption on the surface of the apatite crystal. © 1971 Springer-Verlag.