par Louis, Chantal ;Hootele, Claude
Référence Tetrahedron: asymmetry, 6, 9, page (2149-2152)
Publication Publié, 1995
Article révisé par les pairs
Résumé : Cycloaddition of 2,3,4,5-tetrahydropyridine-1-oxide 1 to (Z)-(R)-vinyl sulfoxides 2a-d proceeds in high yield to give isoxazolidines 3a-d and 4a-d with complete exo selectivity and with 82-98% asymmetric induction. This method provides an efficient synthesis of the enantiomerically pure piperidine alkaloid (+)-sedridine 6a.

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