Résumé : Aims. The study examined the value of contrast echocardiography (CE) in the assessment of left ventricular (LV) wall motion in ventilated patients in comparison with transesophageal (TOE) and standard fundamental transthoracic imaging (SE). Methods. Transthoracic echocardiograms were done in 40 ventilated patients. Wall motion was evaluated using the recommendations of the American Society of Echocardiography on SE, CE and TOE. A visualization score was assigned on a scale of 2-0 for each of 16 segments. The segment was assigned a value of 2 if the segment was seen in both systole and diastole, 1 if seen only in systole or diastole, and 0 if not seen at all. A confidence score was also given for each segment with each technique (unable to evaluate; not sure; sure). The ejection fraction (EF) was estimated visually for each technique, and a confidence score was also applied to the EF. Results. Visualization score 0 was present in 6.2 segments/patient on SE, 1.2 on CE (P<0.0001) and 1.1 on TOE (P<0.0001). An average of 6.5 segments were read with surety on SE, 11.5 on CE (P<0.0001) and 12.3 on TOE (P<0.0001). There was no significant dierence for CE vs TOE. EF was uninterpretable in 32% on SE, 0% on CE (P<0.001) and 0% on TOE (P<0.001). The EF was read with surety in 53% of patients on SE, 88% on CE (P<0.0001) and 93% with TOE (P<0.0001) with no dierence for CE vs TOE. Thus, wall motion was seen with more confidence on CE and TOE. Conclusions. In the ventilated patients with suboptimal transthoracic echocardiograms for the evaluation of the LV function, CE provides image quality of regional and global LV function similar to that achieved with TOE echocardiography. © 2003 The European Society of Cardiology. Published by Elsevier Ltd. All rights reserved.