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Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated beta-cell death.

par Arif, Sefina;Moore, Fabrice ;Marks, Katherine;Bouckenooghe, Thomas ;Dayan, Colin M;Planas, Raquel;Vives-Pi, Marta;Powrie, Jake;Tree, Timothy;Marchetti, Piero;Huang, Guo Cai;Gurzov, Esteban Nicolas ;Pujol-Borrell, Ricardo;Eizirik, Decio L. ;Peakman, Mark
Référence Diabetes (New York, N.Y.), 60, 8, page (2112-2119)
Publication Publié, 2011

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Titre:	Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated beta-cell death.
Auteur:	Arif, Sefina; Moore, Fabrice; Marks, Katherine; Bouckenooghe, Thomas; Dayan, Colin M; Planas, Raquel; Vives-Pi, Marta; Powrie, Jake; Tree, Timothy; Marchetti, Piero; Huang, Guo Cai; Gurzov, Esteban Nicolas; Pujol-Borrell, Ricardo; Eizirik, Decio L.; Peakman, Mark
Informations sur la publication:	Diabetes (New York, N.Y.), 60, 8, page (2112-2119)
Statut de publication:	Publié, 2011
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Adolescent
	Adult
	Animals
	Apoptosis -- drug effects
	CD4-Positive T-Lymphocytes -- immunology
	Cell Line, Tumor
	Cytokines -- physiology
	Diabetes Mellitus, Type 1 -- immunology
	Female
	Humans
	Insulin-Secreting Cells -- drug effects -- pathology
	Insulinoma -- metabolism
	Interleukin-17 -- biosynthesis -- physiology
	Interleukins -- biosynthesis
	Male
	NF-kappa B -- physiology
	Nuclear Receptor Subfamily 1, Group F, Member 3 -- biosynthesis
	Pancreatic Neoplasms -- metabolism
	Rats
	Rats, Wistar
	STAT1 Transcription Factor -- physiology
	Tumor Necrosis Factor-alpha -- physiology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0012-1797
	info:doi/10.2337/db10-1643
	info:pii/db10-1643
	info:scp/80052829943
	info:pmid/21659501
	PMC3142078