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Sequential use of protein kinase inhibitors potentiates their toxicity to melanoma cells: a rationale to combine targeted drugs based on protein expression inhibition profiles.

par Aftimos, Philippe ;Wiedig, Murielle;Langouo Fontsa, Mireille ;Awada, Ahmad ;Ghanem, Ghanem Elias ;Journé, Fabrice
Référence International journal of oncology, 43, 3, page (919-926)
Publication Publié, 2013-09

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Titre:	Sequential use of protein kinase inhibitors potentiates their toxicity to melanoma cells: a rationale to combine targeted drugs based on protein expression inhibition profiles.
Auteur:	Aftimos, Philippe; Wiedig, Murielle; Langouo Fontsa, Mireille; Awada, Ahmad; Ghanem, Ghanem Elias; Journé, Fabrice
Informations sur la publication:	International journal of oncology, 43, 3, page (919-926)
Statut de publication:	Publié, 2013-09
Sujet CREF:	Cancérologie
	Médecine pathologie humaine
	Sciences bio-médicales et agricoles
MeSH keywords:	Cell Line, Tumor
	Gene Expression Regulation, Neoplastic -- drug effects
	Humans
	Janus Kinases -- antagonists & inhibitors
	MAP Kinase Kinase Kinases -- antagonists & inhibitors
	Melanoma -- drug therapy -- genetics -- pathology
	Molecular Targeted Therapy
	Phosphatidylinositol 3-Kinases -- antagonists & inhibitors
	Protein Kinase Inhibitors -- administration & dosage
	Signal Transduction -- drug effects -- genetics
	Transcriptome -- drug effects
	src-Family Kinases -- antagonists & inhibitors
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:1019-6439
	info:doi/10.3892/ijo.2013.2008
	info:scp/84880615410
	info:pmid/23835698