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New 5-Aryl-1H-imidazoles display in vitro antitumor activity against apoptosis-resistant cancer models, including melanomas, through mitochondrial targeting.

par Mathieu, Véronique ;Van Den Berge, Emilie;Ceusters, Justine;Konopka, Tomasz ;Cops, Antonin;Bruyère, Céline ;Pirker, Christine;Berger, Walter;Trieu-Van, Tran;Serteyn, Didier ;Kiss, Robert ;Robiette, Raphael
Référence Journal of medicinal chemistry, 56, 17, page (6626-6637)
Publication Publié, 2013-09

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Titre:	New 5-Aryl-1H-imidazoles display in vitro antitumor activity against apoptosis-resistant cancer models, including melanomas, through mitochondrial targeting.
Auteur:	Mathieu, Véronique; Van Den Berge, Emilie; Ceusters, Justine; Konopka, Tomasz; Cops, Antonin; Bruyère, Céline; Pirker, Christine; Berger, Walter; Trieu-Van, Tran; Serteyn, Didier; Kiss, Robert; Robiette, Raphael
Informations sur la publication:	Journal of medicinal chemistry, 56, 17, page (6626-6637)
Statut de publication:	Publié, 2013-09
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Antineoplastic Agents -- pharmacology
	Apoptosis -- drug effects
	Cell Line, Tumor
	Drug Screening Assays, Antitumor
	Humans
	Imidazoles -- pharmacology
	Melanoma -- pathology
	Mitochondria -- drug effects
	Models, Biological
	Neoplasms -- pathology
	Transcriptome
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
	SCOPUS: ar.j
Langue:	Anglais
Identificateurs:	urn:issn:0022-2623
	info:doi/10.1021/jm400287v
	info:scp/84884276750
	info:pmid/23845202