No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression.

Serretti, Alessandro; Chiesa, Alberto; Calati, Raffaella; Massat, Isabelle; Linotte, Sylvie; Kasper, Siegfried; Lecrubier, Yves; Fink, Martin; Antonijevic, Irina; Forray, Carlos; Snyder, Lenore; Bollen, Joseph; Zohar, Joseph; De Ronchi, Diana; Souery, Daniel; Mendlewicz, Julien

doi:doi/10.1016/j.psychres.2010.11.023

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No influence of PTGS2 polymorphisms on response and remission to antidepressants in major depression.

par Serretti, Alessandro ;Chiesa, Alberto ;Calati, Raffaella ;Massat, Isabelle

;Linotte, Sylvie

;Kasper, Siegfried ;Lecrubier, Yves ;Fink, Martin ;Antonijevic, Irina ;Forray, Carlos ;Snyder, Lenore ;Bollen, Joseph ;Zohar, Joseph ;De Ronchi, Diana ;Souery, Daniel

;Mendlewicz, Julien

Référence Psychiatry research, 188, 1, page (166-169)
Publication Publié, 2011-06

Article révisé par les pairs

Résumé :

In the present study, aimed at investigating whether a set of single nucleotide polymorphisms (SNPs) within PTGS2 gene (rs4648276, rs2066826 and rs689466) could be associated with antidepressant response, remission and treatment resistance in a sample of major depression patients, we did not find evidence supporting any of such associations.

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