par Wathelet, Nathalie 
;Moser, Muriel
Référence Oncoimmunology, 2, 4, page (e23973)
Publication Publié, 2013-04
;Moser, Muriel Référence Oncoimmunology, 2, 4, page (e23973)
Publication Publié, 2013-04
Article révisé par les pairs
| Résumé : | The majority of rodent and human tumors express antigens that can be recognized by T lymphocytes and are infiltrated by immune cells. Although tumor infiltration by T lymphocytes has been associated with a favorable prognosis, the role of dendritic cells (DCs), which may present tumor-associated antigens in an immunogenic or tolerogenic context, remains elusive. Here, we discuss recent observations suggesting that the function of DCs in the tumor microenvironment may impact the spontaneous resistance of neoplasms to chemotherapy as well as treatment outcome. |
