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Identification of the cytochrome P450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes.

par Jacolot, F;Simon, Isabelle ;Dreano, Y;Beaune, P;Riche, C.;Berthou, F
Référence Biochemical pharmacology, 41, 12, page (1911-1919)
Publication Publié, 1991-06

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Titre:	Identification of the cytochrome P450 IIIA family as the enzymes involved in the N-demethylation of tamoxifen in human liver microsomes.
Auteur:	Jacolot, F; Simon, Isabelle; Dreano, Y; Beaune, P; Riche, C.; Berthou, F
Informations sur la publication:	Biochemical pharmacology, 41, 12, page (1911-1919)
Statut de publication:	Publié, 1991-06
Sujet CREF:	Sciences bio-médicales et agricoles
MeSH keywords:	Animals
	Biotransformation
	Cytochrome P-450 Enzyme System -- antagonists & inhibitors -- metabolism
	Drug Interactions
	Humans
	Immunoblotting
	Kinetics
	Methylation
	Microsomes, Liver -- enzymology
	Oxidoreductases, N-Demethylating -- metabolism
	Oxygenases -- metabolism
	Rabbits
	Tamoxifen -- metabolism
	Testosterone -- pharmacology
Note générale:	Journal Article
	Research Support, Non-U.S. Gov't
Langue:	Anglais
Identificateurs:	urn:issn:0006-2952
	info:pii/0006-2952(91)90131-N
	info:pmid/2039544