par Mendlewicz, Julien 
;Sevy, Serge;Brocas, Huguette;Simon, Philippe ;Charon, François;Legros, Sylviane ;Vassart, Gilbert
Référence Lancet, 329, 8544, page (1230-1232)
Publication Publié, 1987
;Sevy, Serge;Brocas, Huguette;Simon, Philippe ;Charon, François;Legros, Sylviane ;Vassart, Gilbert Référence Lancet, 329, 8544, page (1230-1232)
Publication Publié, 1987
Article révisé par les pairs
| Résumé : | Heredity is an important factor in vulnerability to manic depression. A genetic linkage has been demonstrated between manic depression and coagulation factor IX at Xq27 with a TaqI polymorphism at the F9 locus in DNA samples from peripheral leucocytes of manic depressive probands and relatives in 10 informative families. Statistical analysis of the pedigrees gave a maximum lod score of 3·10 at a recombination fraction of 0·11, demonstrating a linkage between a manic depressive locus and the F9 locus in the Xq27 region. © 1987. |
