par Lanternier, Fanny;Pathan, Saad;Vincent, Quentin B;Liu, Luyan;Cypowyj, Sophie;Prando, Carolina;Migaud, Mélanie;Taibi, Lynda;Ammar-Khodja, Aomar;Boudghene Stambouli, Omar;Guellil, Boumediene;Jacobs, Frédérique ;Goffard, Jean-Christophe ;Schepers, Kinda ;Del Marmol, Véronique ;Boussofara, Lobna;Denguezli, Mohamed;Larif, Molka;Bachelez, Hervé;Michel, Laurence;Lefranc, Gérard;Hay, Rod;Jouvion, Gregory;Chretien, Fabrice;Fraitag, Sylvie;Bougnoux, Marie-Elisabeth;Boudia, Merad;Abel, Laurent;Lortholary, Olivier;Casanova, Jean-Laurent;Picard, Capucine;Grimbacher, Bodo;Puel, Anne
Référence The New England journal of medicine, 369, 18, page (1704-1714)
Publication Publié, 2013-10
Référence The New England journal of medicine, 369, 18, page (1704-1714)
Publication Publié, 2013-10
Article révisé par les pairs
Résumé : | Deep dermatophytosis is a severe and sometimes life-threatening fungal infection caused by dermatophytes. It is characterized by extensive dermal and subcutaneous tissue invasion and by frequent dissemination to the lymph nodes and, occasionally, the central nervous system. The condition is different from common superficial dermatophyte infection and has been reported in patients with no known immunodeficiency. Patients are mostly from North African, consanguineous, multiplex families, which strongly suggests a mendelian genetic cause. |